
Ethoxylated hydrogenated castor oil
CAS No. 61788-85-0
Ethoxylated hydrogenated castor oil ( PEG-40 hydrogenated castor oil | Macrogolglycerol hydroxystearate | Castor oil, hydrogenated, polyethoxylated )
产品货号. M28857 CAS No. 61788-85-0
乙氧基化氢化蓖麻油是合成聚乙二醇 (PEG) 与天然蓖麻油的组合。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
1G | ¥340 | 有现货 |
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生物学信息
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产品名称Ethoxylated hydrogenated castor oil
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述乙氧基化氢化蓖麻油是合成聚乙二醇 (PEG) 与天然蓖麻油的组合。
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产品描述Ethoxylated hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions.(In Vivo):Nearly 20% of Ethoxylated hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake. 20% Ethoxylated hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice. Ethoxylated hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females.
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体外实验——
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体内实验——
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同义词PEG-40 hydrogenated castor oil | Macrogolglycerol hydroxystearate | Castor oil, hydrogenated, polyethoxylated
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通路Others
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靶点Other Targets
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受体RORγ
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研究领域——
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适应症——
化学信息
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CAS Number61788-85-0
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分子量——
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分子式——
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : ≥ 100 mg/mL
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Zhang Y, et al. Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J Med Chem. 2019 May 9;62(9):4716-4730.
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